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August 22, 2025International Journal of Molecular MedicineOpen Access

Takotsubo syndrome: Unraveling the mystery behind its triggers (Review)

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Authors

XFXuehui FanYYYuying YuanZHZhida Huang

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Overview

Review reveals underlying mechanisms of takotsubo syndrome, suggesting new therapeutic strategies and implications.

Key Points

  • Takotsubo syndrome triggers involve a complex interplay between emotional and physical stressors, leading to heart dysfunction.
  • Key insights include altered adrenergic receptor distribution and increased catecholamine secretion during TTS episodes.
  • The review analyzes mechanisms like endothelial dysfunction and sympathetic nervous system overstimulation related to TTS.
  • Further investigations are needed to comprehensively understand TTS and enhance prevention and treatment methods.

Cite This Study

Fan et al. (2025) studied this question.

synapsesocial.com/papers/68af73637567bf4f94fed1afhttps://doi.org/10.3892/ijmm.2025.5615
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Takotsubo syndrome in the context of pre-existing non-ischemic cardiomyopathy: mechanistic and clinical implications2026
  2. 2Takotsubo Cardiomyopathy: An Exploration of the Intersection Between Stress, Coronary Dysfunction, and Cardiac Outcomes2025
  3. 3Takotsubo Syndrome in 2025: Evolving Concepts in Pathophysiology, Diagnosis, and Long-Term Management2025 · 7 citations
  4. 4Coronary Microvascular Dysfunction in Stress Cardiomyopathy: At the Heart of the Problem2026
  5. 5Intracranial Triggers of Takotsubo Syndrome2025