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August 22, 2025PLoS ONEOpen Access

Identifying clusters of multimorbid disease and differences by age, sex, and socioeconomic status: A systematic review

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Authors

NMNataysia Mikula-NobleVCVicki CormieRMRebecca McCowan

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Overview

Systematic review investigates disease clusters in multimorbidity, revealing differences by age and socioeconomic status.

Key Points

  • Multimorbidity prevalence shows distinct patterns of disease clusters based on age and socioeconomic factors, highlighting health disparities.
  • From 24,231 papers reviewed, 125 studies were included, identifying 918 unique clusters categorized into 59 groups.
  • Latent Class Analysis was the most utilized method for identifying clusters, appearing in 51 studies throughout the review.
  • Findings suggest the importance of tailoring healthcare services to prevalent disease combinations specific to age and socioeconomic status.

Cite This Study

Mikula-Noble et al. (2025) studied this question.

synapsesocial.com/papers/68af73567567bf4f94fecb60https://doi.org/10.1371/journal.pone.0329794
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