August 22, 2025Open Access

Augment rice ANNEXIN expression to counter planthopper NlAnnexin-like5 as an anti-virulence strategy against a major crop pest

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Augmenting rice annexin expression significantly increases resistance to the brown planthopper pest.
RNA interference of NlAnnexin-like5 decreased feeding performance and survival rate by over 70% in BPH.
Analysis demonstrated that NlAnnexin-like5 displaces OsANN proteins from rice cell membranes to enhance defense.
This anti-virulence strategy could drastically improve crop protection against major agricultural pests.

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RNA interference reduces brown planthopper survival in rice, suggesting annexin expression boosts pest resistance.

Zhang et al. (2025) studied this question.

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