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August 22, 2025Open Access

Assessing demographic and clinical characteristics and healthcare resource utilization of patients with schizophrenia with inadequate response to antipsychotic treatment

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Authors

AHAndre HejaziMBMorgan BronMPM. Mercedes Pérez-Rodríguez

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Overview

Retrospective cohort study shows higher healthcare resource utilization in schizophrenia patients with inadequate antipsychotic response, highlighting the role of social determinants in outcomes.

Key Points

  • Patients with inadequate antipsychotic response had significantly higher psychiatric inpatient visits, indicating greater healthcare needs.
  • Among 408 patients, 32.4% experienced inadequate response to antipsychotics, significantly linked to social challenges like homelessness and unemployment.
  • Analysis of electronic health record data revealed that treatment-resistant schizophrenia patients had considerable differences in healthcare utilization compared to those with adequate response.
  • Social determinants like homelessness and employment status were prominent factors, emphasizing the need for targeted interventions and improved treatment strategies.

Cite This Study

Hejazi et al. (2025) studied this question.

synapsesocial.com/papers/68af707c7567bf4f94fec776https://doi.org/10.21203/rs.3.rs-7158569/v1
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