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August 21, 2025PLoS ONEOpen Access

Improvement in risk prediction for patients with atrial fibrillation and intermediate-risk CHA2DS2-VASc score utilizing highly sensitive cardiac troponin T

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Authors

CSChristian SalbachMYMustafa YıldırımBMBarbara Ruth Milles

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Overview

Retrospective study highlights improved risk prediction for cardiovascular outcomes in patients with atrial fibrillation and intermediate CHA2DS2-VASc score, suggesting better patient management.

Key Points

  • Adding hs-cTnT significantly improves risk prediction for adverse cardiovascular outcomes in patients with AFL.
  • The baseline CHA2DS2-VASc score had poor predictive performance with an AUC of only 0.648 for composite endpoints.
  • Atrial fibrillation patients with intermediate-risk benefited from the addition of hs-cTnT, improving AUC to 0.778.
  • The findings suggest that hs-cTnT could help identify low-risk patients who are unlikely to experience adverse events.

Cite This Study

Salbach et al. (2025) studied this question.

synapsesocial.com/papers/68af70757567bf4f94fec334https://doi.org/10.1371/journal.pone.0330164
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