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August 21, 2025Neurosurgery

12-Month Patient-Reported Outcomes Among Urine Toxicology–Identified Substance Users After Elective Spine Surgery: A Prospective Longitudinal Cohort Study

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Authors

MSManjot SinghASAnna ShlimakMRMargherita Rampichini

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Overview

Prospective cohort study shows opioid use worsens patient-reported outcomes after spine surgery, suggesting insights for rehabilitation strategies.

Key Points

  • Opioid use significantly affected patient-reported outcomes at 12 months, indicating poorer recovery patterns.
  • Overall, 16% reported alcohol use, 23% marijuana use, and 21% opioid use based on urine toxicology results.
  • The study utilized prospective cohort methodology, evaluating outcomes through PROMs and mixed-effects regression analyses.
  • Screening for substance use could optimize decision making and recovery protocols in elective spine surgeries.

Cite This Study

Singh et al. (2025) studied this question.

synapsesocial.com/papers/68af706e7567bf4f94febfe6https://doi.org/10.1227/neu.0000000000003706
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