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August 22, 2025CancersOpen Access

Beyond Detection: Conventional and Emerging Biomarkers in Gastrointestinal Cancers

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Authors

DHDali HanMWMark R. WakefieldYFYujiang Fang

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Overview

This review highlights biomarkers for gastrointestinal cancers, showing liquid biopsies improve early detection and disease management.

Key Points

  • Earlier detection of gastrointestinal cancers could enhance patient prognosis, especially for those with colorectal and gastric cancers.
  • Liquid biopsy biomarkers, including circulating tumor DNA and microRNAs, show promise but face cost and detection rate challenges.
  • This review focuses on both traditional and emerging biomarkers and their role in predicting therapeutic resistance and sensitivity.
  • Limitations of liquid biopsy in low-resource settings suggest further studies are needed to validate its diagnostic efficacy.

Cite This Study

Han et al. (2025) studied this question.

synapsesocial.com/papers/68af706e7567bf4f94febea7https://doi.org/10.3390/cancers17172725
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Also Consider

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  1. 1Emerging Non-Invasive Biomarkers for Early Detection of Gastrointestinal Cancers2025
  2. 2Emerging biomarkers for early cancer detection and diagnosis: challenges, innovations, and clinical perspectives2025 · 84 citations
  3. 3Emerging Biomarkers for Early Cancer Detection: Current Advances and Clinical Applications2026
  4. 4Navigating the Landscape of Liquid Biopsy in Colorectal Cancer: Current Insights and Future Directions2025 · 16 citations
  5. 5Role of Liquid Biopsy as a Future Approach to Early Diagnosis and Management of Colorectal Cancer2025