August 22, 2025Open Access

Seroprevalence of Hepatitis E in General, Hepatic, and Pregnant Populations in Nepal, Bangladesh, and Pakistan: A Systematic Review and Meta-Analysis

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Discussion

Meta-analysis reports 23.8% HEV seroprevalence in general population, highlighting risks for pregnant women and hepatic patients.

Pooled HEV seroprevalence reached 23.8% in the general population, emphasizing a significant health concern.
In pregnant women and hepatic patients, seroprevalence was notably high at 41.2% and 41.8%, respectively.
A systematic review and meta-analysis encompassed 64 studies across Nepal, Bangladesh, and Pakistan to assess HEV prevalence.
High heterogeneity and publication bias in results necessitate cautious interpretation and targeted public health interventions.

Gupta et al. (2025) studied this question.

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