Diagnostic Performance of Imaging Modalities in Persistent or Recurrent Hyperparathyroidism: A Network Meta-Analysis of 18F-Fluorocholine PET/CT, 4D-CT, and Scintigraphy
Network meta-analysis compares diagnostic performance of 18F-fluorocholine, 4D-CT, and scintigraphy in persistent hyperparathyroidism, suggesting a new hierarchy for imaging techniques.
Key Points
18F-fluorocholine PET/CT showed the highest sensitivity at 94.1%, surpassing other imaging methods.
Among 687 patients, 18F-fluorocholine PET/CT ranked superior for per-patient and per-lesion detection in persistent hyperparathyroidism.
A Bayesian bivariate network meta-analysis was used to evaluate the diagnostic performance of various imaging modalities.
These results advocate for revising current diagnostic algorithms to improve surgical outcomes and patient care.