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August 21, 2025Frontiers in PediatricsOpen Access

Clinical characteristics and factors associated with severe COVID-19 among hospitalized pediatric patients: a retrospective cohort study in the Chaoshan region of China

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Authors

XWXianyao WangRMRui MaWZWen‐Zhao Zhong

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Overview

Retrospective cohort analysis identifies predictors of severe COVID-19 in pediatric hospitalized patients, indicating fatigue and hoarseness as key symptoms.

Key Points

  • Severe or critical illness was identified in 32.8% of hospitalized pediatric COVID-19 patients, primarily under 3 years old.
  • Fatigue and hoarseness emerged as significant predictors for severe COVID-19 in children, with fatigue linked to neurological involvement.
  • A retrospective cohort study reviewed clinical data from 287 pediatric patients admitted between December 2022 and August 2023.
  • Vigilance is necessary for young patients with neurological symptoms due to the association with acute necrotizing encephalopathy and mortality.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68af40a1cf1dd9ea359ecb55https://doi.org/10.3389/fped.2025.1627428
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