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July 19, 2025Journal of Neonatal SurgeryOpen Access

Diagnostic Accuracy of Serum Procalcitonin (PCT) as an Early Biomarker of Neonatal Sepsis using Blood Culture as Gold Standard: A Prospective Study

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Authors

SNSumaira NabiMIM. IqbalSMSidra Masood

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Overview

Prospective study finds procalcitonin accurately identifies neonatal sepsis, suggesting improved clinical decisions.

Key Points

  • Serum procalcitonin demonstrated high diagnostic performance with 92% sensitivity and 83% specificity, indicating its reliability.
  • Out of 61 neonates studied, 25 had positive blood cultures, with elevated PCT levels in 23 cases, supporting early diagnosis.
  • The negative predictive value of PCT was 93.8%, making it effective for ruling out neonatal sepsis quickly.
  • This prospective study conducted from January to September 2024 highlights the potential of PCT over traditional methods.

Cite This Study

Nabi et al. (2025) studied this question.

synapsesocial.com/papers/68af40a1cf1dd9ea359ecb0fhttps://doi.org/10.63682/jns.v13i1.8426
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