August 20, 2025NutrientsOpen Access

Moderate Alcohol Consumption and Risk of Depression: A Longitudinal Analysis in Community-Dwelling Older Adults

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Discussion

Longitudinal analysis reveals lower depression risk associated with moderate alcohol consumption in older adults, indicating a J-shaped relationship.

Moderate alcohol consumption is linked to the lowest risk of depression among older adults, confirming a J-shaped association.
Occasional and abstinent drinkers significantly increased the risk of depression by 11% and 17% respectively compared to moderate drinkers.
Analysis included 16,563 community-dwelling older adults participating in the ASPREE trial, employing marginal structural models for accuracy.
Findings suggest that moderate alcohol consumption may mitigate depression risk, but careful adjustment for confounders was crucial.

Mohebbi et al. (2025) studied this question.

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Longitudinal analysis reveals lower depression risk associated with moderate alcohol consumption in older adults, indicating a J-shaped relationship.