Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 1, 2025Singapore Medical JournalOpen Access

Early predictors of rescue therapy and colectomy in acute severe ulcerative colitis

View Full Paper
Ask AI
Bookmark
Share

Authors

SLSamuel Jun Ming LimKCKaina ChenYTYi Yuan Tan

Discussion

Loading...

Member takes

Overview

Retrospective cohort study identifies early predictors for rescue therapy and colectomy in patients with acute severe ulcerative colitis, suggesting risk stratification strategies.

Key Points

  • Rescue therapy was needed in 34.5% of admissions for acute severe ulcerative colitis, revealing significant predictors.
  • Elevated C-reactive protein and CRP–albumin ratio predicted rescue therapy needs, showing relative risks up to 2.37.
  • Retrospective cohort study analyzed 58 admissions for acute severe ulcerative colitis over nearly 20 years, focusing on early biomarkers.
  • Findings highlight the importance of early assessments for better treatment strategies in acute severe ulcerative colitis.

Cite This Study

Lim et al. (2025) studied this question.

synapsesocial.com/papers/68af3e4fcf1dd9ea359eb98ahttps://doi.org/10.4103/singaporemedj.smj-2024-242
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Therapeutic management and risk of colectomy in patients with acute severe ulcerative colitis and previous exposure to anti-TNF drugs: a comparative study of GETECCU2025
  2. 2Editorial: Corticosteroid Responsive Acute Severe Ulcerative Colitis—Revisiting Maintenance Approaches in the Era of Advanced Therapies2025
  3. 3OUTCOMES OF ACUTE SEVERE ULCERATIVE COLITIS IN ELDERLY PATIENTS: A MULTICENTER EXPERIENCE2026
  4. 4Short- and longevity outcome of cyclosporin rescue therapy in severe ulcerative colitis refractory to intravenous corticosteroid treatment2025
  5. 5Outcomes of Outpatient Advanced Therapy Exposed Patients Hospitalized With Severe Ulcerative Colitis.2025