A Systematic Review of Clinical and Experimental Periodontitis Studies Demonstrating the Expression of PPAR-Gamma: A Meta-Analysis and Bioinformatics Approach
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Key Points
Lower levels of PPAR-gamma protein were found in periodontal tissues from animals with periodontitis, highlighting an inflammatory response.
The meta-analysis revealed a need for further evaluation of PPARG mRNA and PPAR-gamma protein levels in periodontal tissues.
Assessment of PPAR-gamma involved multiple methods, including gene expression and protein techniques in both clinical and experimental studies.
Bioinformatics analyses uncovered PPAR-gamma-related molecules involved in the immune response to periodontitis.
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