Prevalence and risk factors for persistent opioid use after thoracic surgery: A retrospective cohort study in a prefecture of Japan

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Persistent opioid use occurred in 3.3% of patients after thoracic surgery, indicating a notable risk of dependence.
Neoadjuvant therapy and thoracotomy emerged as independent risk factors for persistent opioid use in the analysis.
The analysis involved 3,924 patients aged ≥18 who underwent thoracic surgery between October 2012 and September 2021.
Tailored pain management strategies may enhance outcomes for patients identified at higher risk for opioid dependence.

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Retrospective cohort study finds 3.3% experienced persistent opioid use after thoracic surgery, suggesting specific risk factors.

Yokoyama et al. (2025) studied this question.

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