Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 20, 2025Frontiers in GeneticsOpen Access

A metagenome-wide association study of gut microbiota in hepatitis B virus-related cirrhosis in northwest China

View Full Paper
Ask AI
Bookmark
Share

Authors

MFM FengYCYan ChaiJLJ. R. Li

Discussion

Loading...

Member takes

Overview

Cross-sectional analysis reveals gut microbiota alterations in hepatitis B virus-related cirrhosis patients, suggesting potential therapeutic targets.

Key Points

  • HBV-LC patients showed reduced gut microbiota diversity and heightened levels of opportunistic pathogens.
  • Significant changes in clinical indicators, including elevated liver enzymes and altered lipid profiles, were observed.
  • Cross-sectional study involving 43 HBV-LC patients and 43 healthy controls used shotgun metagenomic sequencing.
  • Findings underscore the importance of gut microbiome-targeted therapies for liver health in this region.

Cite This Study

Feng et al. (2025) studied this question.

synapsesocial.com/papers/68af3e42cf1dd9ea359eb29ahttps://doi.org/10.3389/fgene.2025.1619911
View Full Paper
Ask AI
Bookmark
Share