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August 14, 2025Karnataka Pediatric Journal

Immunological conundrum – A paradoxical reaction in tuberculosis

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Authors

SNShobitha NagabushanIMInchara MuralidharamNJNancy V Jeniffer

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Overview

Case report demonstrates resolution of Poncet’s disease symptoms in a 16-year-old girl with abdominal tuberculosis, indicating immune reactions can complicate treatment.

Key Points

  • Complete resolution of symptoms observed after adjusting treatment, with a short steroid course enhancing recovery.
  • A paradoxical response in tuberculosis shows worsening symptoms can occur during effective treatment in some cases.
  • The patient, with abdominal tuberculosis, initially presented with joint swelling and pain diagnosed as Poncet’s disease.
  • This situation highlights the importance of monitoring immune reactions during anti-tubercular treatment and steroid use.

Cite This Study

Nagabushan et al. (2025) studied this question.

synapsesocial.com/papers/68af3e3ccf1dd9ea359eb007https://doi.org/10.25259/kpj_57_2024
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