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August 12, 2025

Effects of electroacupuncture on cognitive impairment and mitophagy mediated by KIF5A/Miro1 pathway in Parkinson's disease mice.

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Authors

MLMengzhu LiJCJiafan ChenMCMengxuan Chen

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Implication

Observational analysis improved cognitive function in Parkinson's disease mice, indicating the KIF5A/Miro1 pathway plays a crucial role.

Key Points

  • Electroacupuncture significantly improved cognitive function in Parkinson's disease mice, enhancing memory and spatial learning.
  • Y-maze and Morris water maze tests showed notable performance improvements in the electroacupuncture group (P<0.01).
  • Analysis of the KIF5A/Miro1 pathway revealed significant changes in mitochondrial morphology and autophagy markers after treatment.
  • This intervention highlights the potential of electroacupuncture in treating cognitive impairment in Parkinson's disease models.

Cite This Study

Li et al. (2025) studied this question.

synapsesocial.com/papers/68af3e3ccf1dd9ea359eafa9https://doi.org/10.13703/j.0255-2930.20250227-k0004
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