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August 12, 2025

Mechanism of acupuncture on cerebral ischemia-reperfusion injury via p53/SLC7A11/GPX4 signaling pathway in rat models.

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Authors

QWQi WangNorthwestern Polytechnical UniversityZHZongliu HouYLYaoyao Liu

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Implication

Observational analysis shows reduced neurological damage in rat models of cerebral ischemia-reperfusion injury, indicating acupuncture's neuroprotective effects via p53 signaling pathway.

Key Points

  • Xingnao Kaiqiao acupuncture significantly alleviates neurological damage in rat models of cerebral ischemia-reperfusion injury.
  • Compared with the model group, the acupuncture group exhibited significantly improved neurological deficit scores and reduced cerebral infarction volume.
  • Analysis employs a rat model with cerebral ischemia-reperfusion injury to evaluate acupuncture's effects on the p53/SLC7A11/GPX4 pathway.
  • These findings highlight acupuncture's potential in neuroprotection, warranting further research in clinical applications.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68af3e3ccf1dd9ea359eaf8fhttps://doi.org/10.13703/j.0255-2930.20240703-k0003
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