Neurochemical biomarkers of amyotrophic lateral sclerosis: recent developments

View Full Paper

Ask AI

Bookmark

Authors

Discussion

Review reveals promising biomarkers like neurofilaments and TDP-43 for amyotrophic lateral sclerosis, indicating potential for improved diagnostics.

Neurofilaments, particularly NFL, are established biomarkers for amyotrophic lateral sclerosis, aiding in diagnosis and prognosis.
Blood phosphorylated tau is linked to lower motor neuron pathology, showing potential as an emerging biomarker for ALS.
Advancements in assays reveal promising methods for quantifying TDP-43 and assessing its role in ALS pathology.
Inflammatory biomarkers like chitinases may serve vital roles in monitoring treatment response targeting neuroinflammation.

Federico Verde (2025) studied this question.

View Full Paper

Ask AI

Bookmark

Review reveals promising biomarkers like neurofilaments and TDP-43 for amyotrophic lateral sclerosis, indicating potential for improved diagnostics.