August 20, 2025Global Spine JournalOpen Access

Multiple Treatment Analysis of Aneurysmal Bone Cysts in Mobile Spine

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Both intralesional injection and Denosumab therapy significantly reduce lesion size in patients with aneurysmal bone cysts.
In a cohort of 27 patients, complete symptomatic resolution was achieved in 10 of 14 patients treated with injection therapy.
Open surgery yielded an 83.3% recovery rate, with minor neurological deficits remaining in two patients post-operatively.
Despite the different treatments, no significant differences were found in recurrence rates or complications among the cohorts.

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Retrospective cohort study evaluates outcomes of open surgery, doxycycline injections, and Denosumab in patients with spinal aneurysmal bone cysts.

Liu et al. (2025) studied this question.

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Retrospective cohort study evaluates outcomes of open surgery, doxycycline injections, and Denosumab in patients with spinal aneurysmal bone cysts.