Evaluation of the skeletal muscle index in predicting toxic complications of antitumor drug therapy in patients with gastric cancer

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Correlation analysis demonstrates skeletal muscle index predicts toxicity severity in gastric cancer patients, suggesting its clinical utility.

Presence of sarcopenia correlates with increased toxicity following chemotherapy in gastric cancer patients.
Patients with lower skeletal muscle index showed a statistically significant increase in anemia and vomiting severity.
Assessment method used included computed tomography to diagnose sarcopenia and CTCAE for adverse effect severity.
Implications highlight the need to incorporate skeletal muscle index in evaluating treatment risks for gastric cancer patients.

Петроченко et al. (2025) studied this question.

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View Full Paper

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Authors

Correlation analysis demonstrates skeletal muscle index predicts toxicity severity in gastric cancer patients, suggesting its clinical utility.

Presence of sarcopenia correlates with increased toxicity following chemotherapy in gastric cancer patients.
Patients with lower skeletal muscle index showed a statistically significant increase in anemia and vomiting severity.
Assessment method used included computed tomography to diagnose sarcopenia and CTCAE for adverse effect severity.
Implications highlight the need to incorporate skeletal muscle index in evaluating treatment risks for gastric cancer patients.

Петроченко et al. (2025) studied this question.

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