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August 19, 2025AntioxidantsOpen Access

The Role of Antioxidants in Male Fertility: A Comprehensive Review of Mechanisms and Clinical Applications

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Authors

DBDavid BouhadanaMPMarie-Hélène Godin PagéDMDebbie Montjean

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Overview

Comprehensive review highlights how antioxidants affect sperm quality in male infertility, suggesting potential clinical applications.

Key Points

  • Supplementation with specific antioxidants may improve sperm parameters and fertility outcomes, with variable results based on dosage and individual conditions.
  • Oxidative stress significantly impacts male reproductive health by affecting sperm functionality, indicating a need for targeted antioxidant treatments.
  • This comprehensive review evaluates mechanisms of reactive oxygen species and highlights key clinical studies on antioxidants in treating male infertility.
  • Antioxidant supplementation has potential benefits but requires careful patient selection and further clinical trials to standardize treatment protocols.

Cite This Study

Bouhadana et al. (2025) studied this question.

synapsesocial.com/papers/68af35e9cf1dd9ea359ea272https://doi.org/10.3390/antiox14081013
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Oxidative Stress, Antioxidants, Gut Microbiota and Male Fertility2025
  2. 2Reductive stress and the role of antioxidants in male infertility: a narrative review2025
  3. 3The mechanism of oxidative stress in asthenozoospermia and antioxidant strategies: a review2025
  4. 4Beneficial Effects of Resveratrol on Testicular Functions: Focus on Its Antioxidant Properties2025
  5. 5Antioxidant therapy for preserving and restoring male reproductive health2025