August 19, 2025PharmacyOpen Access

Pharmacist-Led Interventions for Polypharmacy Management in Older Adults: A Systematic Review of Strategies and Outcomes in the United Kingdom and the Republic of Ireland

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Discussion

Systematic review shows pharmacist-led strategies enhance prescribing quality for older adults, suggesting need for expanded roles.

Pharmacist-led interventions significantly improved prescribing quality and reduced medication-related risks, yet failed to lower hospitalizations.
Twelve of fourteen studies reported positive outcomes, including reductions in potentially inappropriate medications and adverse drug reactions.
Analysis included randomized trials and observational designs following PRISMA 2020 guidelines for studies conducted from 2010 to 2024.
Key barriers to success involve low uptake of pharmacist recommendations and short follow-up periods, indicating need for policy reform.

McGrory et al. (2025) studied this question.

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