Enhanced Pain Management in Total Knee Arthroplasty: A Retrospective Analysis on Intraoperative Cryo-Neurolysis

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Retrospective analysis shows intraoperative cryo-neurolysis lowers pain scores in TKA, suggesting improved recovery and less opioid use.

Intraoperative cryo-neurolysis significantly reduced postoperative pain scores to zero for all patients by Month 6.
Median pain scores decreased markedly from 2 on Day 1 to 0 by Month 3, with a high statistical significance (p < 0.00001).
Retrospective cohort study involving 34 TKA patients assessed pain, opioid use, and mobility over six months using various analysis methods.
Findings indicate potential benefits for multimodal pain management in TKA, arguing for further randomized trials to explore opioid use impacts.

Elfekky et al. (2025) studied this question.

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View Full Paper

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Authors

Retrospective analysis shows intraoperative cryo-neurolysis lowers pain scores in TKA, suggesting improved recovery and less opioid use.

Intraoperative cryo-neurolysis significantly reduced postoperative pain scores to zero for all patients by Month 6.
Median pain scores decreased markedly from 2 on Day 1 to 0 by Month 3, with a high statistical significance (p < 0.00001).
Retrospective cohort study involving 34 TKA patients assessed pain, opioid use, and mobility over six months using various analysis methods.
Findings indicate potential benefits for multimodal pain management in TKA, arguing for further randomized trials to explore opioid use impacts.

Elfekky et al. (2025) studied this question.

View Full Paper

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Bookmark