Associations of glycaemia‐related risk factors with dementia and cognitive decline in individuals with type 2 diabetes: A systematic review and meta‐analysis
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Key Points
Hypoglycaemia significantly increases the risk of all-cause dementia by 49% and Alzheimer's disease by 31%.
The pooled effect size for hypoglycaemia and dementia risks varied minimally, suggesting consistent risks across demographics.
Thirty studies showed that longer diabetes duration and HbA1c levels correlate with higher dementia risk.
Limited evidence was found linking glycaemia-related factors to cognitive decline, indicating more research is needed.
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Implication
Systematic review demonstrates higher dementia risk linked to hypoglycaemia and HbA1c in type 2 diabetes.