Systematic review highlights severe adenovirus infections in children, indicating increased hospitalization and morbidity rates.
Key Points
Severe adenovirus infections are linked to increased hospitalization in children under 5 years, with pneumonia being a common complication.
Out of 2026 articles screened, 12 original studies met inclusion criteria, illustrating the disease burden of adenovirus infections in healthy children.
Observational analysis aggregated clinical data from multiple studies conducted predominantly in Asia, emphasizing geographic variances in disease prevalence.
Understanding adenovirus symptoms and co-infections is essential, as they may worsen disease severity, suggesting a need for better treatment protocols.