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August 19, 2025Panacea Journal of Medical SciencesOpen Access

Coagulation profile and Platelet indices as a predictive marker in Gestational Hypertension and Pre-eclampsia- A case-control study of 260 cases

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Authors

SSSweta SwetaMAMayank AgrawalRSRajeev Sen

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Overview

Case-control analysis reveals decreased platelet count and prolonged PT and APTT in women with gestational hypertension.

Key Points

  • Pregnant women with gestational hypertension showed significant decreases in platelet count compared to the control group, indicating a predictive relationship.
  • Prothrombin Time (PT) and Activated Partial Thromboplastin Time (APTT) were significantly prolonged in women with pregnancy-induced hypertension.
  • Comparative study design analyzed platelet parameters and coagulation profiles across 260 pregnant women categorized into PIH and normotensive groups.
  • Findings highlight the need for rapid platelet count screening in pregnancy-induced hypertension to assess the risk of coagulopathy.

Cite This Study

Sweta et al. (2025) studied this question.

synapsesocial.com/papers/68af35d5cf1dd9ea359e97fehttps://doi.org/10.18231/pjms.v.15.i.2.326-329
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Changes in Blood Coagulation Parameters and Platelet Indices in Pregnancies with Gestational Hypertension and Preeclampsia2024
  2. 2Platelet Indices among Women with Pre-eclampsia attending at a Tertiary Care Hospital – A Case Control Study2025
  3. 3Evaluating Platelet Indices as Biomarkers in Gestational Hypertension: Clinical Implications and Future Perspectives - A Narrative Review2026
  4. 4Haemostatic Function and Predictive Values for Pre-Eclampsia Severity of Pregnant Women in a Rural West African Town2025
  5. 5Significance of platelet parameters in pre-eclampsia: A prospective cross-sectional study from a tertiary care center in North India2025