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August 18, 2025World Journal of Gastroenterology

Important role of tumor deposits and negative lymph nodes in prognosis of N1c colorectal cancer patients

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Authors

ZSZhi‐Gang SunSCShaoxuan ChenBSBai-Long Sun

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Overview

Retrospective analysis identifies NLNTD as a significant prognostic factor in N1c colorectal cancer, suggesting implications for treatment strategies.

Key Points

  • Tumor deposits and negative lymph nodes significantly influence prognosis in N1c colorectal cancer patients, impacting overall survival.
  • Five-year disease-free survival was 73.5% for patients with NLNTD > 6 versus 50% for those with NLNTD ≤ 6, indicating strong prognostic value.
  • Kaplan-Meier analysis assessed disease-free survival, with NLNTD calculated as NLN/(TD + 1), suggesting combinatory roles of factors.
  • The findings highlight the need for stratifying patients based on NLNTD to enhance treatment approaches, emphasizing high-risk groups.

Cite This Study

Sun et al. (2025) studied this question.

synapsesocial.com/papers/68af33efcf1dd9ea359e9612https://doi.org/10.3748/wjg.v31.i31.109857
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