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August 18, 2025OralOpen Access

The Obesity–Periodontitis Axis: Microbial Mechanisms and Clinical Implications

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Authors

EAEdson AraújoLFLorena Abreu FernandesTMTamires Szeremeske Miranda

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Overview

Narrative review reveals microbial dysbiosis links obesity and periodontitis, suggesting common inflammatory pathways.

Key Points

  • Obesity significantly alters the composition of the oral microbiome, leading to reduced diversity and increased pathogenic bacteria.
  • Key evidence illustrates that periodontal pathogens invade the gut and impair barrier function, promoting systemic inflammation.
  • This narrative review analyzes peer-reviewed studies to explore interactions between microbial dysbiosis and inflammation.
  • Understanding the obesity-periodontitis axis may support the development of customized treatment strategies for patients.

Cite This Study

Araújo et al. (2025) studied this question.

synapsesocial.com/papers/68af33efcf1dd9ea359e94cehttps://doi.org/10.3390/oral5030061
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