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July 22, 2025Disease and DiagnosisOpen Access

Exploring the Relationship Between Clinical and Paraclinical Findings and the Severity of Ulcerative Colitis and Disease Extension

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Authors

ABAyoub BashamEEEbrahim EvaziSTSaeed Hosseini Teshnizi

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Overview

Cross-sectional study finds indicators of disease severity in ulcerative colitis, suggesting clinical monitoring improvements.

Key Points

  • Severe ulcerative colitis was linked to higher levels of fecal calprotectin and ESR, highlighting disease severity.
  • Fecal calprotectin levels were elevated in patients with greater colon involvement, indicating disease extension.
  • Targeted immunotherapies and abdominal pain were significant indicators of disease severity, underscoring clinical relevance.
  • The study included 299 patients, with results suggesting specific clinical markers for monitoring ulcerative colitis.

Cite This Study

Basham et al. (2025) studied this question.

synapsesocial.com/papers/68af33e9cf1dd9ea359e93a2https://doi.org/10.34172/ddj.1663
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evaluation Of Relationship Between Endoscopic Activity Index and Inflammatory Indicators Such as Fecal Calprotectin, C-Reactive Protein to Albumin Ratio, Neutrophil to Lymphocyte Ratio, Platelet to Lymphocyte Ratio in Ulcerative Colitis Patients2025
  2. 2Prevalence and Predictors of Gastrointestinal Infections Among Patients With Acute Severe Ulcerative Colitis and Those in Remission: A Cross-Sectional Study2026
  3. 3Clinical characteristics and predictive biomarkers for ulceration in ischemic colitis: A case-control study2025
  4. 4OUTCOMES OF ACUTE SEVERE ULCERATIVE COLITIS IN ELDERLY PATIENTS: A MULTICENTER EXPERIENCE2026
  5. 5Correlation between clinical and histopathological scoring systems in Egyptian patients with ulcerative colitis (single center study)2025