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August 19, 2025Open Access

Impact of Early Initiation of Antimicrobials on Acute Kidney Injury Due to Sepsis

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Authors

MNMina G. NashedHOHamdy OmarAEAhmed A. Elilly

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Overview

Prospective analysis shows timely antimicrobial therapy improves kidney function recovery in septic patients, indicating a critical need for prompt treatment.

Key Points

  • Timely initiation of antimicrobials significantly reduces the incidence of acute kidney injury in sepsis patients, which improves recovery outcomes.
  • Patients receiving antibiotics within 4 hours had a 73.1% improvement in kidney function compared to 18.29% for those delayed beyond 8 hours.
  • This prospective analysis included 297 patients admitted to an intensive care unit with acute kidney injury due to sepsis.
  • Highlighting the need for prompt antimicrobial treatment can aid in optimizing care for septic patients and improve renal outcomes.

Cite This Study

Nashed et al. (2025) studied this question.

synapsesocial.com/papers/68af33e9cf1dd9ea359e9322https://doi.org/10.21203/rs.3.rs-7294034/v1
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