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August 19, 2025

Peripheral Blood Mononuclear Cell Gene Expression Signatures Predict Long-term Survivorship in Canine DLBCL

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Authors

KRKirthana RaoZRZechuan RaoAHAi Huang

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Overview

Clinical trial shows gene expression in PBMCs predicts survival outcomes in dogs with DLBCL, suggesting future treatments can be tailored accordingly.

Key Points

  • Long-term survivorship in dogs with DLBCL relates significantly to specific gene expression signatures, enhancing predictive capabilities.
  • Key biomarkers like CCR9 and CD1E revealed distinct survival outcomes, with early responders showing unique gene patterns.
  • Assessment of PBMC gene expression utilized NanoString technology for comprehensive analysis across treatment phases.
  • Findings highlight the potential of gene expression testing for personalized treatment plans in canine lymphoma cases.

Cite This Study

Rao et al. (2025) studied this question.

synapsesocial.com/papers/68af33e9cf1dd9ea359e91aahttps://doi.org/10.21203/rs.3.rs-7110482/v1
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