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August 13, 2025The Open AIDS JournalOpen Access

A Longitudinal Analysis of CD4+ T-Cell Count Dynamics in Treated HIV-Infected Individuals in the United States

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Authors

KMKatrina MottJTJ. ThomasZLZhiwei Liu

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Overview

Retrospective cohort analysis reveals individual trajectories of CD4+ T-cell count in HIV-infected individuals, suggesting significant variability.

Key Points

  • Almost half of individuals experienced a 30% increase or decrease in CD4+ T-cell counts during the follow-up period.
  • For those experiencing a decrease, 38.4% had two or more subsequent counts, yet 24.3% did not recover to baseline levels.
  • This retrospective cohort study analyzed health claims data among adults with suppressed viral load over a decade.
  • These findings highlight the meaningful heterogeneity in CD4+ T-cell count changes despite sustained viral suppression.

Cite This Study

Mott et al. (2025) studied this question.

synapsesocial.com/papers/68af33d5cf1dd9ea359e87b7https://doi.org/10.2174/0118746136401702250811211403
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