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January 1, 2025MOJ Biology and MedicineOpen Access

Isolation of compound and molecular docking studies of Wedelia calendulacea extract fractions against dengue vector, Aedes aegypti

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Authors

MBMathalaimuthu BaranitharanSJS JeyaparvathiMPMarsosang Pongen

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Overview

Isolation of phenolic compounds and docking studies showed 100% ovicidal activity against Aedes aegypti, suggesting new dengue control methods.

Key Points

  • Identified phenolic compound shows 100% mortality against Aedes aegypti at 10 ppm, highlighting potential for mosquito control.
  • Molecular docking revealed interaction with juvenile hormone-binding protein, indicating a viable target for intervention.
  • Mass spectra analysis found nineteen compounds in the extract, with a key focus on phenol, 2-methyl-5-(1-methylethyl).
  • Findings support further exploration of Wedelia calendulacea compounds as effective alternatives for mosquito control.

Cite This Study

Baranitharan et al. (2025) studied this question.

synapsesocial.com/papers/68af2ef6cf1dd9ea359e724ahttps://doi.org/10.15406/mojbm.2025.10.00238
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