August 17, 2025FoodsOpen Access

A Novel Lytic Salmonella Phage Harboring an Unprecedented Tail-Protein Domain Combination Capable of Lysing Cross-Host-Transmitted Salmonella Strains

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Phage gmqsjt-1 lysed 69.23% of Salmonella strains, including 75.56% that were resistant.
Genomic analysis showed the presence of unique tail proteins and no virulence genes in phage gmqsjt-1.
Multiplex PCR helped identify Salmonella strains from 4458 samples, underscoring the diversity of sources.
Results indicate phage gmqsjt-1 could significantly mitigate Salmonella contamination in food sources, enhancing safety.

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Implication

Observational analysis reveals a lytic phage inhibits cross-host transmission of multidrug-resistant Salmonella, suggesting new antibiotic alternatives.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/68af2eeacf1dd9ea359e6a9a https://doi.org/10.3390/foods14162850

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Implication

Observational analysis reveals a lytic phage inhibits cross-host transmission of multidrug-resistant Salmonella, suggesting new antibiotic alternatives.

A Novel Lytic Salmonella Phage Harboring an Unprecedented Tail-Protein Domain Combination Capable of Lysing Cross-Host-Transmitted Salmonella Strains

Key Points

Discussion

Implication

Cite This Study

A Novel Lytic Salmonella Phage Harboring an Unprecedented Tail-Protein Domain Combination Capable of Lysing Cross-Host-Transmitted Salmonella Strains

Key Points

Discussion

Implication

Cite This Study