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August 18, 2025Current OncologyOpen Access

Targeting Senescence in Oncology: An Emerging Therapeutic Avenue for Cancer

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Authors

SMSatoru MeguroSMSyunta MakabeKYKei Yaginuma

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Overview

Observational analysis highlights the potential of senotherapeutics and therapy-induced senescence in cancer, suggesting new strategies for treatment.

Key Points

  • Targeting senescence may enhance cancer therapy effectiveness, offering a dual approach to manage tumor progression and treatment resistance.
  • Ongoing clinical trials are exploring the role of senotherapeutics alongside senescence-inducing therapies in various cancer types.
  • Therapy-induced senescence can influence cancer outcomes, raising the importance of understanding its effects in oncology treatments.
  • Research indicates a strong connection between cellular senescence and aging-related cancer progression, with implications for new therapeutic avenues.

Cite This Study

Meguro et al. (2025) studied this question.

synapsesocial.com/papers/68af2edecf1dd9ea359e6442https://doi.org/10.3390/curroncol32080467
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