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August 18, 2025Frontiers in NutritionOpen Access

Enhanced versus standard fortification of pasteurized donor human milk for growth in very low birth weight infants: a randomized controlled trial

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Authors

COChengsi OngAWAnng Anng WongSWSiew Tin Wong

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Overview

Randomized controlled trial shows enhanced fortification improves length and head circumference in VLBW infants, suggesting better growth outcomes.

Key Points

  • Impaired weight gain between fortified donor human milk methods showed no significant difference, indicating similar outcomes for very low birth weight infants.
  • Length and head circumference z-scores improved with enhanced fortification compared to standard methods, showing potential for better growth rates.
  • Enhanced fortification required less high calorie formula supplementation compared to standard, demonstrating an efficient feeding strategy for vulnerable infants.
  • No significant differences were found in rates of bronchopulmonary dysplasia or retinopathy of prematurity, indicating similar safety profiles between methods.

Cite This Study

Ong et al. (2025) studied this question.

synapsesocial.com/papers/68af2edecf1dd9ea359e6356https://doi.org/10.3389/fnut.2025.1582519
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