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August 16, 2025Current Issues in Molecular BiologyOpen Access

Unlocking the Anti-Breast Cancer Potential of Aralia chinensis L.

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Authors

JXJuan XueLLLei LiYSYongqian Shu

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Overview

Analysis uncovers anti-breast cancer effects of Aralia chinensis components in serum, highlighting multi-target pathways and activity.

Key Points

  • TSAC inhibited proliferation and migration of MCF-7 cells, revealing its anti-breast cancer properties.
  • Molecular docking showed strong binding between components and cancer-related targets, including EGFR and Src.
  • Analysis of 486 compound targets linked critical pathways like the PI3K-Akt signaling to the treatment effect.
  • Integration of serum pharmacochemistry and network pharmacology underpins drug discovery for breast cancer therapy.

Cite This Study

Xue et al. (2025) studied this question.

synapsesocial.com/papers/68af2d89cf1dd9ea359e606chttps://doi.org/10.3390/cimb47080662
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