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August 14, 2025Indian Journal of Pathology and MicrobiologyOpen Access

Primary central nervous system lymphomas in three “blue books” and correlation of recently defined primary large B-cell lymphoma of immune-privileged sites: Single-center experience

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Authors

OŞOnur ŞahinIBIrem Guvendir BakkalogluAKAli Kaya

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Overview

Single-center experience correlates primary central nervous system lymphomas with B-cell lymphomas, indicating diagnostic challenges.

Key Points

  • Ten of the fifteen patients with primary central nervous system lymphomas were diagnosed with immune-privileged large B-cell lymphomas.
  • Overall, 66.6% of patients showed characteristics consistent with immune-privileged large B-cell lymphoma, highlighting common findings.
  • Fluorescence in situ hybridization analysis revealed no MYC and BCL2 rearrangements in seven cases, supporting specific diagnoses.
  • This study underscores the importance of classification systems in accurately diagnosing primary central nervous system lymphomas.

Cite This Study

Şahin et al. (2025) studied this question.

synapsesocial.com/papers/68af2d89cf1dd9ea359e600chttps://doi.org/10.4103/ijpm.ijpm_401_24
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