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August 7, 2025Journal of Composites ScienceOpen Access

Microwave-Assisted Hydrothermal Synthesis of Cu/Sr-Doped Hydroxyapatite with Prospective Applications for Bone Tissue Engineering

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Authors

DRDiana-Elena RadulescuBVBogdan Ştefan VasileOVOtilia Ruxandra Vasile

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Overview

Laboratory process successfully improves biocompatibility and antibacterial activity of hydroxyapatite using Cu2+ and Sr2+ ions for bone applications.

Key Points

  • Hydroxyapatite samples showed significant antimicrobial properties, especially those doped with 5% Cu and Sr, enhancing their suitability for biomedical applications.
  • Synthesis used eggshells and mussel shells as CaO sources, presenting an eco-friendly approach to creating hydroxyapatite materials.
  • MC3T3-E1 osteoblast cells showed good cellular viability when exposed to both undoped and doped hydroxyapatite samples, suggesting effective biocompatibility.
  • The study demonstrates a successful microwave-assisted hydrothermal method for synthesizing doped hydroxyapatite with promising mechanical stability.

Cite This Study

Radulescu et al. (2025) studied this question.

synapsesocial.com/papers/68af2b5ccf1dd9ea359e4463https://doi.org/10.3390/jcs9080427
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Microwave Effects on Double‐Decomposition‐Produced Hydroxyapatite: X‐ray Diffraction, Infrared Spectroscopy, Hirshfeld Surface, and Molecular Docking Studies2025 · 6 citations
  2. 2The potential of green mussel shells as a source of hydroxyapatite for biomedical applications: A comparative study with commercial hydroxyapatite2025
  3. 3Unraveling an Organic Soluble Precursor‐Based Low‐Temperature Synthetic Strategy to Impurity‐Free Pristine and Transition Metal Doped Lead Apatites2025 · 1 citations
  4. 4Synthesis and Characterization of Submicron Hydroxyapatite from Calcium Nitrate Tetrahydrate: Implications of pH Variations in the Precipitation Process2025
  5. 5Nano CeO<sub>2</sub>‐Doped Hydroxyapatite: A Multifunctional Biomaterial with Enhanced Physical, Mechanical, and Biological Performance2025