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August 8, 2025International Journal of Molecular SciencesOpen Access

Cardio-Pulmonary Features of Long COVID: From Molecular and Histopathological Characteristics to Clinical Implications

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Authors

GCGiovanni CimminoSDSaverio D’EliaMMMariarosaria Morello

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Overview

Emerging evidence demonstrates persistent cardiovascular and pulmonary alterations in long COVID patients, indicating a need for integrated diagnostics and management.

Key Points

  • Patients with long COVID exhibit significant cardiovascular and pulmonary complications, including varied inflammatory responses and potential tissue damage.
  • Elevated levels of pro-inflammatory cytokines, such as IL-6, contribute to a prothrombotic state and heightened risk of chronic complications.
  • Diagnostic strategies should incorporate molecular and histopathological assessments to effectively evaluate cardio-pulmonary health post COVID-19.
  • Recognizing the interrelation between pulmonary fibrosis and cardiac dysfunction underscores the necessity for multidisciplinary care approaches.

Cite This Study

Cimmino et al. (2025) studied this question.

synapsesocial.com/papers/68af2b56cf1dd9ea359e43e0https://doi.org/10.3390/ijms26167668
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