July 31, 2025Journal of PharmacyOpen Access

Formulation and evaluation of topical gels containing Phyllanthus muellerianus leaf extract using various gelling agents

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Wounds treated with formulations A4 and C5 showed significantly decreased wound area and increased re-epithelialization over 15 days post-injury.
Phyllanthus muellerianus gels exhibited satisfactory physicochemical properties and no detected dermal toxicity in tests.
Gels were formulated using four different gelling agents, maintaining stability and safety throughout the evaluation period.
Phytochemical screening revealed the presence of tannins, glycosides, and saponins in the leaf extract, supporting its medicinal properties.

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Topical gels utilizing phyllanthus muellerianus show significant wound healing in trials, indicating potential as natural alternatives.

Antwi et al. (2025) studied this question.

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