August 8, 2025BiomedicinesOpen Access

The Role of Pharmacogenetic Biomarkers in Pain

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Discussion

Narrative review highlights pharmacogenetic biomarkers' role in pain management, suggesting they may enhance treatment safety and effectiveness.

Genetic variants significantly influence patients' responses to analgesics, impacting pain relief and adverse effects.
Evidence supports that pharmacogenetic screening improves analgesic effectiveness and reduces opioid complications.
Narrative review includes analysis of genetic polymorphisms affecting pharmacokinetics and pharmacodynamics of pain medications.
Incorporating pharmacogenetic biomarkers into clinical practice may enhance patient outcomes and safety in pain management.

Silva et al. (2025) studied this question.

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Narrative review highlights pharmacogenetic biomarkers' role in pain management, suggesting they may enhance treatment safety and effectiveness.