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August 17, 2025Frontiers in OncologyOpen Access

Global burden of cancer in women, 1990–2021: a systematic analysis from the GBD 2021 study

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Authors

YMYun MaoYGYebo GaoYHYuting He

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Overview

Systematic analysis reveals rising breast cancer rates and ongoing cervical cancer challenges in low-income regions, highlighting key health disparities.

Key Points

  • Breast cancer incidence surged by 28% since 1990, accounting for 2.08 million new cases in 2021, driven by lifestyle factors and higher socio-demographic index.
  • Cervical cancer remains a significant issue in low-income countries, correlating negatively with socio-demographic index, despite a decline in global mortality rates.
  • Analysis utilized data from the Global Burden of Disease Study, examining trends in incidence, mortality, and disability-adjusted life years across 204 countries.
  • Focus on priority interventions like HPV vaccination and low-cost screenings is essential to address disparities and improve healthcare access.

Cite This Study

Mao et al. (2025) studied this question.

synapsesocial.com/papers/68a35495234c60ad5c20f16bhttps://doi.org/10.3389/fonc.2025.1633894
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Also Consider

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  1. 1Breast cancer burden (1990–2040) in individuals aged 55 and above: a GBD 2021 analysis of global trends, sex-specific risk factors, and intervention impact2025 · 3 citations
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  4. 4Global determinants of gynecologic cancer incidence and mortality: A cluster‐based analysis with predictive insights2025
  5. 5Global, regional, and national disease burden and economic costs of cervical cancer (1991–2021): a multidimensional data synthesis analysis2025 · 5 citations