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August 17, 2025

The application of network pharmacology and molecular docking to investigate the mechanisms underlying the therapeutic effects of Salidroside in acute lung injury, along with validation through animal experiments

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Authors

MZMin ZhaoLFLiuxiang FengWLWenhua Li

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Overview

Analysis identifies Salidroside's impact on inflammatory factors in acute lung injury, suggesting therapeutic potential.

Key Points

  • Salidroside significantly reduced inflammatory factors in an acute lung injury model, alleviating tissue damage.
  • In vivo experiments showed a marked decrease in IL-6 and TNF-α levels in the Salidroside-treated group compared to controls.
  • Using network pharmacology, potential molecular targets and TNF signaling pathways related to Salidroside were identified.
  • The findings support the application of Salidroside as a therapeutic candidate for treating acute lung injury.

Cite This Study

Zhao et al. (2025) studied this question.

synapsesocial.com/papers/68a3548d234c60ad5c20ee7ahttps://doi.org/10.21203/rs.3.rs-6773277/v1
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