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August 17, 2025BiomoleculesOpen Access

A Brief Review of MicroRNA Profiling in Human Prostate Cancer Tissues and Plasma

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Authors

GKGeorgios KallinikasAEAmin M. EktesabiCVChirag M. Vaswani

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Overview

Literature review uncovers critical biomarkers in prostate tissues and plasma, suggesting new diagnostic pathways.

Key Points

  • MicroRNA profiles show potential for early prostate cancer detection, improving current diagnostic methods.
  • From 318 articles screened, 219 miRNAs were identified in tissue and 12 in plasma, highlighting key biomarkers.
  • Analysis of GEO datasets reveals common miRNAs between tissue and plasma, indicating their liquid biopsy potential.
  • Functional evidence of oncogenic and tumor-suppressive miRNAs suggests pathways for future prostate cancer treatments.

Cite This Study

Kallinikas et al. (2025) studied this question.

synapsesocial.com/papers/68a35335234c60ad5c20e7b1https://doi.org/10.3390/biom15081156
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