The Role of Baseline PET/CT Parameters in Predicting Treatment Response in Patients with Locally Advanced Rectal Cancer Undergoing Total Neoadjuvant Therapy
Retrospective study indicates baseline PET/CT parameters predict treatment response in locally advanced rectal cancer, suggesting their importance in treatment decisions.
Key Points
Baseline metabolic parameters from PET/CT may predict treatment response in patients with locally advanced rectal cancer.
The analysis included 52 patients, revealing significant differences in tumor volume between responders and non-responders.
Lower metabolic tumor volume and total lesion glycolysis were associated with a complete response to total neoadjuvant therapy.
Findings highlight the potential of PET/CT parameters as prognostic tools in treatment planning for rectal cancer.