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August 4, 2025NutrientsOpen Access

Effect of Polyphenol-Rich Interventions on Gut Microbiota and Inflammatory or Oxidative Stress Markers in Adults Who Are Overweight or Obese: A Systematic Review and Meta-Analysis

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Authors

ÁGÁlvaro González‐GómezMCMartina CantoneAGAna María García‐Muñoz

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Overview

Systematic review reveals polyphenol interventions modify gut microbiota and reduce oxidative stress in overweight adults, suggesting health benefits.

Key Points

  • Polyphenol supplementation significantly reduced circulating lipopolysaccharides, indicating improved gut barrier function.
  • Significant enhancement in catalase activity suggests boosted antioxidant defense from polyphenol interventions.
  • Gut microbiota analysis showed increased butyrate and acetate, demonstrating potential prebiotic effects of polyphenols.
  • No significant changes were observed in BMI or body weight, highlighting the complexity of metabolic responses.

Cite This Study

González‐Gómez et al. (2025) studied this question.

synapsesocial.com/papers/689a0f86e6551bb0af8d0b7chttps://doi.org/10.3390/nu17152468
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