August 2, 2025

Genomic Regions and Variant Analysis Reveal Candidate Genes Associated with Age at First Service in Chinese Holstein Heifers

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Identified three genomic regions linked to age at first service, explaining a total of 0.91% of genetic variance.
A genome-wide association study analyzed 3,686 Chinese Holstein heifers using over 7.9 million SNPs for AFS.
ANAPC4 was highlighted as a putative causal gene influencing puberty and reproductive efficiency in heifers.
The findings suggest potential improvements in heifer breeding strategies, reducing economic costs in dairy production.

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Genome-wide association study identified key genes affecting age at first service in Holstein heifers, suggesting new breeding strategies.

Pan et al. (2025) studied this question.

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Genome-wide association study identified key genes affecting age at first service in Holstein heifers, suggesting new breeding strategies.